地五养肝胶囊抗肝纤维化的作用及其机制*

陈露, 李瀚旻

中西医结合肝病杂志 ›› 2025, Vol. 35 ›› Issue (3) : 385-388.

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PDF(3514 KB)
中西医结合肝病杂志 ›› 2025, Vol. 35 ›› Issue (3) : 385-388. DOI: 10.3969/j.issn.1005-0264.2025.003.027
综述

地五养肝胶囊抗肝纤维化的作用及其机制*

  • 陈露1, 李瀚旻1,2△
作者信息 +

Anti-hepatic fibrosis effect of Diwu Yanggan capsule Liver Capsules and its mechanism

  • CHEN Lu1, LI Han-min1,2△
Author information +
文章历史 +

摘要

肝纤维化作为慢性肝病向肝硬化和肝癌转变的关键阶段,有效阻止或逆转肝纤维化进展对慢性肝病患者的预后具有重要影响。积极治疗可以延缓甚至逆转早期肝纤维化,间充质干细胞是具有较大潜力的治疗方式之一。在前期临床及实验研究中已证实地五养肝胶囊可防治肝纤维化,本文基于间充质干细胞探讨地五养肝胶囊防治肝纤维化的潜在作用机制。

Abstract

Liver fibrosis is the central link in the transformation of chronic liver disease to cirrhosis and liver cancer, and it is crucial to effectively stop or reverse the progression of liver fibrosis. Early liver fibrosis can be slowed down or even reversed with treatment. Mesenchymal stromal cells have great potential in the treatment of liver fibrosis. Diwu Yanggan capsule has been proved to prevent liver fibrosis in previous clinical and experimental studies, and this paper explores the possible role of Diwu Yanggan capsule in preventing liver fibrosis and its mechanism based on mesenchymal stem cells.

关键词

地五养肝胶囊 / 肝纤维化 / 间充质干细胞

Key words

Diwu Yanggan capsule / liver fibrosis / mesenchymal stromal cells

引用本文

导出引用
陈露, 李瀚旻. 地五养肝胶囊抗肝纤维化的作用及其机制*[J]. 中西医结合肝病杂志, 2025, 35(3): 385-388 https://doi.org/10.3969/j.issn.1005-0264.2025.003.027
CHEN Lu, LI Han-min. Anti-hepatic fibrosis effect of Diwu Yanggan capsule Liver Capsules and its mechanism[J]. Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases, 2025, 35(3): 385-388 https://doi.org/10.3969/j.issn.1005-0264.2025.003.027
中图分类号: R575   

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基金

*武汉市卫健委中医药科研项目(No.WZ22Q30);国家自然科学基金项目(No.81973669);国家中医临床研究基地(湖北)重点病种研究项目(No.JDZX2015172);李瀚旻湖北中医名师传承工作室资助项目(鄂卫生计生办通〔2018〕32号);
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